Nowadays, fashion accessories have moved out of the closet and are not limited to designer clothes and shoes. Bags also play an essential part in our style statement. More so, you must agree that bags are just not limited to suitcases and side bags to carry critical stuff. With modern concepts and flourishing designs, a gym tote bag is available in various shapes, sizes, designs, and materials, making it a style statement. Be it any purpose, occasion, or requirement; tote bags are a must essential for everyone. Let’s explore the reasons why you should have a tote bag for yourself:

A Bag for Every Occasion

Many amongst us, especially women, prefer different bags for different occasions. It is also true that designer bags are not cheap, and how many can you stock in your wardrobe. The easiest solution to this has a beautifully designed tote bag. It’s durable, efficient, and yet stylish to suit any occasion. These bags are not only functional but also fashionable. They are available in a different variety or quality like leather and canvas; they complement your stylish looks and make for everyday handbags.

Versatility, Durable and Re-Usable

Any number of uses you can think of, a gym tote bag is capable of fitting all. It can be used as beach bags, work bags, office bags, school bags, gym bags, shopping bags, laptop bags, or baby bags. It is the only bag you can use for multi-purpose. Tote bags have gained prominent popularity due to their durability and long-lasting endurance. These bags if taken proper care of can last for years especially if it is made of leather. Another great advantage of possessing a tote bag is its capability of being re-used multiple times, regardless of its style and size. Having made for nothing specific, these bags can be used for various purposes.

The Best Choice for Gifts

We all want to thank our invitees after any celebration, by giving out a little something. The next time considers giving totes as party favors or gifts. Available in various shapes, sizes, materials, and designs choose the ones that suit your requirement. It becomes sometimes challenging to decide on what to opt for and also should fit in the budget.

The Safest and the Most Stylish way to take your Laptop around, and Mothers can put all baby stuff in a gym tote bag

If you want to flaunt your style in your workplace, then tote laptop bags are the best. Along with being stylish and durable, it can carry all your accessories and your Laptop. Tote bags for laptops give your professional attire a different look and be convenient and comfortable to carry.

With a tote bag around the shoulder, moms need not worry about leaving anything behind because of the lack of space in the bag. Carry all baby essentials from feeding bottles to diapers and extra clothes and towels in a single bag. These bags are inexpensive, practical, cute, multi-purpose and eco-friendly.

The blood that stays in the umbilical cord and placenta after birth is known as cord blood. The umbilical cord is clamped and severed after the baby is born, according to the birthing plan agreed upon with the doctor, leaving an average of 80–120 milliliters, or about 1/3 to 1/2 cup, of blood within. A surgical needle is used to extract the blood remaining in the cord and placenta into a collecting bag. Even though the amount of blood taken appears to be little, it includes millions of adult stem cells that can build the blood and immune system. We identify, harvest, and store these stem cells in the hopes of one day using them to cure illness or other medical ailments.

Cord tissue is the insulating layer that surrounds the umbilical cord’s vessels. The umbilical cord will be clamped and cut after birth, and a portion of the cord, generally four inches in length, can be preserved. The cord tissue seems to be transparent and jelly-like. It includes lipids, white cells, and stem cells and provides insulation for the umbilical cord’s two arteries and one vein. It contains epithelial and endothelial stem cells, although mesenchymal stem cells are more abundant. The nervous system, sensory organs, circulatory tissues, skin, bone, cartilage, and other tissues can all be formed from stem cells. Cord tissue banking, like cord blood banking, is a type of biological insurance in which parents save their baby’s stem cells for future therapies. The following are the two primary advantages of storing both cord blood and cord tissue:

• to have a larger number of stem cells from the same child

• to have a variety of cell types.

Difference in Treatments

Because each kind of stem cell is abundant in cord blood and cord tissue, it seems logical that they may be used to treat different illnesses or ailments. Both hematopoietic stem cells in the cord blood and mesenchymal stem cells in the cord tissue can be employed to help repair, regenerate, or cure a range of illnesses, although the problems and diseases they treat seldom overlap. Cord blood has been used in humans for more than 25 years, and it is the only one of the two that has been approved by the FDA for use in regular treatments. Leukemias, lymphomas, anemias, and hereditary metabolic abnormalities can all be treated with it. Clinical trials are also being conducted on cord blood for the treatment of more advanced diseases including autism, cerebral palsy, diabetes, eczema, stroke.

Clinical experiments are still being conducted on the possible future use of mesenchymal stem cells, such as those found in cord tissue, but the results thus far have been highly encouraging. Heart and kidney illness, Lou Gehrig’s disease (ALS), autoimmune disease, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, wound healing, and even sports injuries are all being treated with them.

Cell growth and division require the production of new proteins. This also applies to cancer cells. In a new study published in the journal Science Progress, researchers at the Carolinska Institute studied the protein eIF4A3 and its role in cancer cell growth. This study shows that by blocking or reducing the production of this protein, other processes can lead to the cessation of growth and cell division and ultimately death of cancer cells.

The normal cell division of the body is carefully controlled and genes in the cell are regulated as they begin and stop cell division.

Sometimes this balance is broken and cells continue to divide unchecked. After a while, a small percentage of cells begin to develop, and cancer may be about to form.

“When a cell grows, among other things, it produces new proteins by converting the cell’s DNA information into mRNA, which forms the basis for protein production. The cell also needs to make ribonucleic acid for the cell’s small factory, the ribosome. The ribosome is responsible for the production of protein,” said Mikael Lindström, associate professor and collaborator in the research group of Professor Jiri Bartek in the Department of Medical Biochemistry and Biophysics at the Karolinska Institute, who conducted the research.

In this study, the team investigated cultured cancer cells and cancer tissues, in which the expression of eIF4A3 protein was higher than that of normal tissues.

By adding synthetic small molecules, which can later be further developed into finished drugs, the production of eIF4A3 can be examined. The researchers then found two different changes in cancer cells.

Dimitris Kanellis, lead author of the study and a postdoctoral fellow in the Department of Medical Biochemistry and Biophysics, said: “First, we found that blocking eIF4A3 activates the protein p53, a protein important in fighting cancer cells.”

However, one challenge for many types of tumors is that the positive function of the p53 protein is counteracted by another protein, MDM2.

“Interestingly, we note that blocking eIF4A3 also implies a change in MDM2 protein. Dimitris Kanellis continued: “This change helps maintain and strengthen p53 and may be beneficial when we want to inhibit cancer cell growth.” The main conclusion of the study suggests that deletion or inhibition of eIF4A3 activates p53 and alters the manufacturing process of proteins by disrupting ribosome biogenesis, thereby inhibiting the growth of cancer cells.

The understanding of the importance of eIF4A3 protein opens new opportunities for better and more effective treatment of cancer patients.

“The findings are very relevant because this targeted therapy may represent a new possible chemotherapeutic approach, for example in colon cancer, where cancer cells usually have high levels of ribosomes and rapid growth. Another example is sarcomas, cancers of the supporting tissues of the human body, which we know sometimes produce too much MDM2. This increases the chance of a more effective treatment,” Mikel-LrdSr. Om and Professor Jiri Bartek said.

These studies provide an important basis for further research. However, since the study was mainly conducted in cultured cancer cells and clinical tumor material, it remains to be seen how blocking eIF4A3 will affect the growth of cancer in vivo.

“There may also be synergy between compounds that block eIF4A3 and drugs that we will now further investigate that have been used to treat cancer.”

They are so naive that they engage in risky and impulsive conduct such as playing in the dirt, not washing their hands frequently, touching unhygienic things, etc. It is very common for a kid to get sick from viral infections. So, it is necessary to teach children how to wash their hands with soap and water or with a hand sanitizer at regular intervals to avoid germs contamination.

How do germs spread among children?

Kids are more prone to catch germs in the following ways-

Getting in contact with a sick or about to be a sick person.
Germs can also spread when kids touch their dirty diapers.
Harmful bacterias are also present in the surroundings including food and water. If your kid touches contaminated food or water then he/she is likely to transmit disease into his/her body.
Some common surfaces such as furniture, computers, etc., can be germ-ridden. Children can catch diseases from them.

To avoid transmission, you must teach your kids to wash their hands properly.

Best ways to educate kids to wash their hands properly-

You can teach children by demonstrating. Small children learn best by watching and doing the same. The hearing will not work as they are usually in their world and may not pay attention to it.
Make the kids practise every technique until they master it.
Teach one technique at a time to make them grasp easily.
Try to build their interest in handwashing by reading healthy stories, following hand hygiene advertisements and billboards. This will reinforce the habit of handwashing among children.
You can make your kids watch hygienic videos and learn the importance of handwashing.
Come up with a game for the kids where they will learn at the same time

Which infections can be prevented by washing hands with soap and water or a sanitizer?

Several harmful infections can be prevented by the simple act of washing hands whether with water and soap or a hand sanitizer. Common flu, cold, hepatitis A and bronchitis are some of the everyday diseases found in kids. Children need to wash their hands as a safety measure to control the spread of these diseases into their bodies.

How to clean hands- With a liquid hand sanitizer?

Apply some sanitizer on one hand
Rub over both hands including surfaces between fingers.
Now let it dry

When should children clean their hands?

After playing outside
Before and after eating
After playing with animals
After coughing and sneezing
After using restrooms
After coming home from school

Conclusion

Teaching kids to wash hands at an early age is developing a healthy lifelong habit. Try some attractive incentive policies and rewards or fun activities to remind them to wash their hands. Make sure they carry sanitizers wherever they go. This way they will learn to keep their hands clean while having fun.