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The Benefits of Having a Gym Tote Bag

Nowadays, fashion accessories have moved out of the closet and are not limited to designer clothes and shoes. Bags also play an essential part in our style statement. More so, you must agree that bags are just not limited to suitcases and side bags to carry critical stuff. With modern concepts and flourishing designs, a gym tote bag is available in various shapes, sizes, designs, and materials, making it a style statement. Be it any purpose, occasion, or requirement; tote bags are a must essential for everyone. Let’s explore the reasons why you should have a tote bag for yourself:

A Bag for Every Occasion

Many amongst us, especially women, prefer different bags for different occasions. It is also true that designer bags are not cheap, and how many can you stock in your wardrobe. The easiest solution to this has a beautifully designed tote bag. It’s durable, efficient, and yet stylish to suit any occasion. These bags are not only functional but also fashionable. They are available in a different variety or quality like leather and canvas; they complement your stylish looks and make for everyday handbags.

Versatility, Durable and Re-Usable

Any number of uses you can think of, a gym tote bag is capable of fitting all. It can be used as beach bags, work bags, office bags, school bags, gym bags, shopping bags, laptop bags, or baby bags. It is the only bag you can use for multi-purpose. Tote bags have gained prominent popularity due to their durability and long-lasting endurance. These bags if taken proper care of can last for years especially if it is made of leather. Another great advantage of possessing a tote bag is its capability of being re-used multiple times, regardless of its style and size. Having made for nothing specific, these bags can be used for various purposes.

The Best Choice for Gifts

We all want to thank our invitees after any celebration, by giving out a little something. The next time considers giving totes as party favors or gifts. Available in various shapes, sizes, materials, and designs choose the ones that suit your requirement. It becomes sometimes challenging to decide on what to opt for and also should fit in the budget.

The Safest and the Most Stylish way to take your Laptop around, and Mothers can put all baby stuff in a gym tote bag

If you want to flaunt your style in your workplace, then tote laptop bags are the best. Along with being stylish and durable, it can carry all your accessories and your Laptop. Tote bags for laptops give your professional attire a different look and be convenient and comfortable to carry.

With a tote bag around the shoulder, moms need not worry about leaving anything behind because of the lack of space in the bag. Carry all baby essentials from feeding bottles to diapers and extra clothes and towels in a single bag. These bags are inexpensive, practical, cute, multi-purpose and eco-friendly.

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Create Your Dream Team in Business and Sustain it

No successful business is a result of individual excellence. It is the entire team of professionals that makes a business rise above the zenith. Being an entrepreneur you must be well aware of how important is a team in Business. Now that you have to create your dream team for your dream business, here I present some very useful tips that I have summed up in this article after a rigorous research. It is my firm belief that an entrepreneur can learn a lot from successful sports team about team building. Team sports teach a lot about team building. Below are some of the key points-

1. Team up with the best: If you want to create the best business team then you must team up with the best. Never acknowledge the people you hire as your employees rather acknowledge them as your teammates. No matter for which function you are hiring the people (whether management or operations), hire the best. Never compromise with the talent of your teammates. Many entrepreneurs often stumble at this stage. They don’t hire people as talented as them or more as they fear that they might understand the entire game and might prove to e a threat to the company. However it is a very bad move. According to successful entrepreneurs, one must hire people smarter than them i.e. A class people must hire A+ class people.

2. Keep updating teammates’ skills: It is very important to catch up with time. If you want your team to improve, allow your teammates to update their skills. Buy them updated skills enhancement training courses. For example if your accountant already knows how to use Sage 50 Accounts software then buy him a Sage IAB Qualification training course for another upgraded version of the software.

3. Lend them your vision: Ask any cricket team that has won a Worldcup or any other athletic team that has won an Olympic gold, their players will tell you that they always had the vision of achieving, what they have. It is very important for creating your dream team that you lend your vision to your teammates. No matter what they do in the business, they all must know what the final goal of the company is and how their efforts matter. This gives the teammates a sense of direction and responsibility.

4. Communicate well with the team: Communication is a very important aspect of creating and sustaining a business team. Remember, communication doesn’t only mean to deliver messages it also includes receiving the messages. Communication is a two way process. Give your teammates equal opportunity to share their thoughts and ideas. You never know which idea might click you and give wings to the business. Use software for effective communication like Sage ACT and also provide sage online training to the teammates as to how to use the software effectively. You got to keep updating their skills.

5. Value teammates’ skills: Always value your teammates’ skills. Remember you hired them for a reason after seeing something in them. Acknowledge that each member of the team is vital for the success of your team.

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New Findings on Cancer Cell Growth

Cell growth and division require the production of new proteins. This also applies to cancer cells. In a new study published in the journal Science Progress, researchers at the Carolinska Institute studied the protein eIF4A3 and its role in cancer cell growth. This study shows that by blocking or reducing the production of this protein, other processes can lead to the cessation of growth and cell division and ultimately death of cancer cells.

The normal cell division of the body is carefully controlled and genes in the cell are regulated as they begin and stop cell division.

Sometimes this balance is broken and cells continue to divide unchecked. After a while, a small percentage of cells begin to develop, and cancer may be about to form.

“When a cell grows, among other things, it produces new proteins by converting the cell’s DNA information into mRNA, which forms the basis for protein production. The cell also needs to make ribonucleic acid for the cell’s small factory, the ribosome. The ribosome is responsible for the production of protein,” said Mikael Lindström, associate professor and collaborator in the research group of Professor Jiri Bartek in the Department of Medical Biochemistry and Biophysics at the Karolinska Institute, who conducted the research.

In this study, the team investigated cultured cancer cells and cancer tissues, in which the expression of eIF4A3 protein was higher than that of normal tissues.

By adding synthetic small molecules, which can later be further developed into finished drugs, the production of eIF4A3 can be examined. The researchers then found two different changes in cancer cells.

Dimitris Kanellis, lead author of the study and a postdoctoral fellow in the Department of Medical Biochemistry and Biophysics, said: “First, we found that blocking eIF4A3 activates the protein p53, a protein important in fighting cancer cells.”

However, one challenge for many types of tumors is that the positive function of the p53 protein is counteracted by another protein, MDM2.

“Interestingly, we note that blocking eIF4A3 also implies a change in MDM2 protein. Dimitris Kanellis continued: “This change helps maintain and strengthen p53 and may be beneficial when we want to inhibit cancer cell growth.” The main conclusion of the study suggests that deletion or inhibition of eIF4A3 activates p53 and alters the manufacturing process of proteins by disrupting ribosome biogenesis, thereby inhibiting the growth of cancer cells.

The understanding of the importance of eIF4A3 protein opens new opportunities for better and more effective treatment of cancer patients.

“The findings are very relevant because this targeted therapy may represent a new possible chemotherapeutic approach, for example in colon cancer, where cancer cells usually have high levels of ribosomes and rapid growth. Another example is sarcomas, cancers of the supporting tissues of the human body, which we know sometimes produce too much MDM2. This increases the chance of a more effective treatment,” Mikel-LrdSr. Om and Professor Jiri Bartek said.

These studies provide an important basis for further research. However, since the study was mainly conducted in cultured cancer cells and clinical tumor material, it remains to be seen how blocking eIF4A3 will affect the growth of cancer in vivo.

“There may also be synergy between compounds that block eIF4A3 and drugs that we will now further investigate that have been used to treat cancer.”

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